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Study of the geometry in a 3D flow-focusing device
Microfluidics and Nanofluidics
20
, 40 (
2016
)
Authors
Elena Castro-Hernández
Maarten Kok
Michel Versluis
David Fernández Rivas
BibTeΧ
@Article{Castro-Hernández2016, author="Castro-Hern{\'a}ndez, Elena and Kok, Maarten P. and Versluis, Michel and Fernandez Rivas, David", title="Study of the geometry in a 3D flow-focusing device", journal="Microfluidics and Nanofluidics", year="2016", volume="20", number="2", pages="40", abstract="We present a numerical and experimental study on a non-planar three-dimensional design of a microfluidic flow-focusing device for the well-controlled generation of monodisperse micron-sized droplets. Three relevant geometric parameters were identified: the distance between the inner inlet channel and the outlet channel, the width of the outlet channel, and its length. Simulation data extracted from a full parameter study and finite element simulations yielded four optimum designs that were then fabricated using soft lithography techniques. Under the predicted operating conditions, micro-droplets of a size of {\$}{\$}{\{}{\backslash}sim{\}}1{\backslash},{\backslash}upmu {\backslash}text {\{}m{\}}{\$}{\$} ∼ 1 $\mu$ m in diameter are obtained from a channel {\$}{\$}50{\backslash},{\backslash}upmu {\backslash}text {\{}m{\}}{\$}{\$} 50 $\mu$ m in width. This work represents an important breakthrough in the practical use of flow-focusing devices delivering a ratio of constriction to droplet size of 50 times, with the advantage of reduced clogging of the micro-channel, greatly improving the control and reliability of the device.", issn="1613-4990", doi="10.1007/s10404-016-1708-3", url="http://dx.doi.org/10.1007/s10404-016-1708-3" }
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