Physics of Fluids - Publications

Surface nanodroplet-based nanoextraction from sub-milliliter volumes of dense suspensions

Open Access
Lab on a Chip 21, 2574–2585 (2021)

Authors

	Jae Bem You
	Detlef Lohse
	Xuehua Zhang

BibTeΧ

@Article{D1LC00139F,
author ="You, Jae Bem and Lohse, Detlef and Zhang, Xuehua",
title  ="Surface nanodroplet-based nanoextraction from sub-milliliter volumes of dense suspensions",
journal  ="Lab Chip",
year  ="2021",
volume  ="21",
issue  ="13",
pages  ="2574-2585",
publisher  ="The Royal Society of Chemistry",
doi  ="10.1039/D1LC00139F",
url  ="http://dx.doi.org/10.1039/D1LC00139F",
abstract  ="A greener analytical technique for quantifying compounds in dense suspensions is needed for wastewater and environmental analysis{,} chemical or bio-conversion process monitoring{,} biomedical diagnostics{,} and food quality control{,} among others. In this work{,} we introduce a green{,} fast{,} one-step method called nanoextraction for extraction and detection of target analytes from sub-milliliter dense suspensions using surface nanodroplets without toxic solvents and pre-removal of the solid contents. With nanoextraction{,} we achieve a limit of detection (LOD) of 10‚àí9 M for a fluorescent model analyte obtained from a particle suspension sample. The LOD is lower than that in water without particles (10‚àí8 M){,} potentially due to the interaction of particles and the analyte. The high particle concentration in the suspension sample{,} thus{,} does not reduce the extraction efficiency{,} although the extraction process was slowed down up to 5 min. As a proof of principle{,} we demonstrate the nanoextraction for the quantification of model compounds in wastewater slurry containing 30 wt% solids and oily components (i.e. heavy oils). The nanoextraction and detection technology developed in this work may be used in fast analytical technologies for complex slurry samples in the environment{,} industrial waste{,} or in biomedical diagnostics."}